구강캔디다증 환자의 항진균 치료
Antifungal Therapy in Patient with Oral Candidiasis
김해영, 강재국, 임영관, 김병국, 김혜은, 조혜중, Qioachu Sun, 안규현, Shuhan Shi, 김옥준,
소속 상세정보
김해영 ( Kim Hae-Yong ) - 전남대학교 치의학전문대학원 구강병리학교실
강재국 ( Kang Jae-Kook ) - 전남대학교 치의학전문대학원 구강병리학교실
임영관 ( Im Yeong-Gwan ) - 전남대학교 치의학전문대학원 구강내과학교실
김병국 ( Kim Byung-Gook ) - 전남대학교 치의학전문대학원 구강내과학교실
김혜은 ( Kim Hye-Eun ) - 전남대학교 치의학전문대학원 구강병리학교실
조혜중 ( Cho Hye-Joung ) - 전남대학교 치의학전문대학원 구강병리학교실
( Qioachu Sun ) - 전남대학교 치의학전문대학원 구강병리학교실
안규현 ( Ahn Kyu-Hyeon ) - 전남대학교 치의학전문대학원 구강병리학교실
( Shuhan Shi ) - 전남대학교 치의학전문대학원 구강병리학교실
김옥준 ( Kim Ok-Joon ) - 전남대학교 치의학전문대학원 구강병리학교실
KMID : 0829220170410020079
Abstract
The aim of this study was to examine the effects and the sensitivity of antifungal therapy for patients with oral candidiasis and to investigate the relationship among the signs & symptoms of patients and the ratio change of Candida species to antifungal therapy. Candida fungus culture test with ChromeIDTM Candida agar (CAN2) was carried out more than twice for 10 patients who visited Oral Medicine department of Chonnam National University Dental Hospital during the period from Dec. 2015 to Aug. 2016. After culturing the smear sample before and after antifungal therapy in ChromeIDTM Candida agar (CAN2), the number of colonies was counted to compare. Patients were divided into 5 group according to the therapeutic effects of the antifungal agents used: 1) high susceptibility to nystatin, 2) low susceptibility to nystatin, 3) high susceptibility to fluzonazole, 4) low susceptibility to fluzonazole, and 5) increased ratio of new Candida species. Although nystatin is used as first-line therapy in oral candidiasis, it is desirable to use fluconazole if patients had a history of the low sensitivity to nystatin or chemotherapy. Even if the patient's symptoms and signs are improved, there is a possibility of oral candidiasis recurring, so that clinicians should be careful during the treatment with antifungal agents.
키워드
Antifungal therapy; Oral candidiasis; Smear
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